【心动的文书】针对NUS项目要求，深挖本科背景，通过PS突出个人能力

It is the documentary, Beautiful Chemistry, that introduced me to the world of Chemistry. By means of microscopical techniques and digital technology, each chemical reaction is presented vividly and explicitly. Since then, I have been deeply enchanted by diversified forms and miraculous variations of various substances during their formations. Marveling at such a magical microscopic world, I am fascinated with Chemistry and have developed my learning interest in this discipline.【以《美丽化学》这个纪录片为切入点，陈述化学吸引我之处：我着迷于物质形成过程中的多样化的形态和奇迹般的变化；并表达对于化学的研究兴趣】As I learned more in college, I incisively sensed that Chemistry is an inseparable component of everything we can see. From the vibration of an atom to the throb of an organism, Chemistry permeates the whole process and researches the formation and evolution of macroscopic substances.【随着学习的深入，陈述对于化学更深层次的理解：小到一粒电子的跃迁、一颗原子的振动，大到有机生命体的搏动，化学始终贯穿其中，探索着宏观物体的形成与演化】Hence, embracing a great passion for Chemistry, I persist in pursuing higher education in this appealing domain to contribute to Chemistry-related research and application.【最后，再次强调对于化学的热爱和研究兴趣，表达想要深造的强烈愿望】

讲座/书籍/电影/课程/研究项目等等，都是可以作为很好的契机，用于开篇第一段的兴趣起源，来引出申请者对于xx专业的思考和探索兴趣

注意点：往往很多同学会在这一段中花大量篇幅去陈述课程/项目中做的客观内容，其实不然，有关这个契机的客观陈述，只需一两句简单带过，交代清楚是什么/做了什么即可，更重点的部分应该是「我」从中得思考什么/对于专业有了什么更深的认识，即通过个人观点的展开，向招生官展示学术洞察力。

In my college study, I never slacked off for a moment but made unremitting endeavors to prepare myself for your rigorous postgraduate training. Academically speaking, I have laid a solid knowledge foundation involving inorganic chemistry, organic chemistry, analytical chemistry, and physical chemistry. Specialized courses deepened my understanding of chemical characterization means and enabled me to use various chemical methodologies and techniques to analyze ingredients and structures of substances.【课程角度：陈述化学学科基础】Simultaneously, with expertise in mathematics, statistics, materials science, and physics, I have been able to conduct rigorous experiments and precise data analysis and calculation.【展现数理知识基础】Technically speaking, I proactively participated in diverse experiments, research, and competitions, which enhanced my problem analysis and experimental operation abilities and cultivated my critical thinking, teamwork spirit, and meticulousness.【能力角度：凸显实验技能，批判性思维，团队合作和严谨的实验态度】With sufficient preparation in knowledge and skill, I am looking forward to embarking on my postgraduate journey in the next period of my life.

本科积累部分，主要从专业课，实验，科研项目等方面来展现申请者的专业知识和研究能力

From May 2021 to May 2022, I led my team to participate in College Students’ Science and Technology Entrepreneurship Training Program: Research on Gene Detection Method based on Triple Helix Molecular Beacon.【开头简单交代清楚研究的课题，时间等基本信息】Taking the KRAS gene as the detection target, we introduced its DNA complementary sequence into the Triple Helix Molecular Beacon and designed a signal transduction probe (STP) chain capable of generating the G-quadruplex. Then, we designed three cDNA chains matching the target in varying degrees and probed into their advantages, respectively. As a result, a new cDNA chain, called cDNA-4, was produced with a part of base sequences optimized. Through the performance analysis of the G-quadruplex, I proposed to replace the STP-Probe chain with a new-found chain named 22-AG because of its more vigorous fluorescence intensity.【分层次陈述研究中的几个关键步骤】The biggest challenge of our research was that the testing data of fluorescence intensity was unstable. Hence, changing the experimental conditions, we set several control groups for comparison, summarized the similarities of experimental data acquired in different turns, and got conclusions. The bonding strength between the target chain and the cDNA chain was stronger than that between the Probe-chain and cDNA chain. The annealing of the DNA solution was crucial to reinforce the triple helix between the cDNA-4 chain and the STP-Probe chain. In the subsequent experiment, we found the root cause for the unstable data—the light source for a fluorescence spectrophotometer had been used for too long, resulting in the instability of the fluorescence intensity. We took the G-quadruplex/ heme enzyme complex as the second output signal and carried out the colorimetric detection. Hard work pays off. We illustrated the bonding strength between the 22-AG chain and ThT by the fluorometric/colorimetric dual-signal test, thereby proving the strong bonding strength between the target chain and cDNA chain.【描述遇到的困难及其解放方案和最终结果】Lasting for one year, this research project was indeed a huge challenge for us. Despite that, this research deepened my understanding of abstruse chemical principles and enabled me to apply knowledge more flexibly, ponder issues more thoroughly, and conduct experiments more rigorously. In addition, thanks to this rewarding experience, I deeply realized that we should seek the essence of dizzying phenomena and universalities of complex data to sum up orderly and reliable experiment results. The acquisitions and experience I gained from this project will be conducive to my future study.【强调能力的提升，陈述研究心得】

科研经历的陈述，可以分步骤展开重点研究内容，也可以着眼于某个困难的发现与解决，亦或是叙述某个创新点的提出与实践，这些都是巧妙的写作思路。

Enjoying a good reputation globally, the National University of Singapore is my dream school, and the M.Sc. in Chemical Sciences is my optimal choice.【赞誉学校声誉的同时，明确自己对于贵校研究生项目的向往】Your postgraduate program aims to equip students with advanced knowledge and skills pertaining to recent developments in Chemical Science and help them succeed in Chemistry R & D and relevant industries.【强调自己对于项目主旨的关注】I am very interested in your well-designed modules, like Bioanalytical Chemistry, Topics in Supramolecular Chemistry, and Emerging Concepts in Drug Discover. Through course studies, I will have the chance to explore various domains of Chemistry to obtain interdisciplinary knowledge and master professional experimental and analytical methods and tools as well.【具体列出几门专业课程，并表达期望从中获得的知识和能力】If I have the honor to be accepted, I will not only concentrate on the course learning but devote myself to academic research, paving the way for my future development.

择校部分从学校声望，项目重点和感兴趣的课程三方面展开，在表达「我」对于贵校的研究生项目向往的同时，也能展示「我」对于项目的充分了解。

注意点：除了以上三个角度，同学们在写择校原因时，也可以仔细浏览项目官网，找到一些研究中心，实验室，重点科研项目等，以此为出发点，表达想加入研究团队进行深入探索的愿望。

As the COVID-19 epidemic has spread worldwide in recent years, I am inclined to pursue a doctoral degree in my intended research orientation—medicinal chemistry.【深造计划：攻读药物化学领域的博士】After graduation, I hope to enter a top-ranking biochemistry institute and engage in drug research and discovery. In the long term, I plan to join the R & D department in a biochemical high-tech enterprise, hoping to realize my self-value in my career path.【从长短期两方面来陈述自己的职业发展规划】In spite of the intensified competition for applying to your esteemed program, I have embraced a steadfast determination to study at your world-renowned university.【最后再表达一下想要深造的决心和愿望】

02 总结

这个研究生项目偏好具有化学以及化学相关学科背景的学生，因此在个人陈述的撰写中，需要着重突出自己化学知识背景和研究技能。除此之外，可以在经历的陈述中，展现批判性思维，团队合作，严谨性，学术洞察力等软技能，这些也是项目看重的品质。